Sprycel sluggish bowels

We really are all so different with these TKIs! I remember on the old LLS having hysterical posts on Gleevec sharts! I was never so regular as I was on Sprycel. However, during the years before CML, especially during pregnancy, I discovered the miracle of psyllium seeds (mixed in warm apple juice). Then Metamucil made taking it so much easier. Try a tablespoon or so once or twice a day and see how that works for you.

After my last colonoscopy in April, my doctor's nurse practitioner said I could use Miralax up to 4 times a day if needed. So, I tried it once a day for a few days and that was way too much! Good luck!